PROPEL® Steroid-Releasing Implant

PROPEL is the first and only product in sinus surgery clinically proven with Level 1-A evidence to maintain surgical results.1

PROPEL provides meaningful benefits to patients: PROPEL maintains the opening created during surgery by reducing post-operative scarring, inflammation, polyposis and middle turbinate lateralization.  Reducing such scarring and inflammation is essential to improve long-term outcomes and reduce the need for revision surgery2,3

Download the Propel Patient Information Brochure 
Download the Propel Post-Operative Care Brochure 

How It Works:

Patient Testimonials:

https://youtu.be/tQA_sghwnnI

Safety & Efficacy – Evaluated in Three Prospective Multi-Center Clinical Trials totaling 205 patients

  1. A prospective, randomized, controlled, double-blind Pilot study4, recognized with the 2010 Maurice Cottle Research Award honoring best clinical or basic science by the American Rhinologic Society
  2. The ADVANCE single-cohort study5 assessed safety, endoscopic outcomes and demonstrated improved patient symptom scores out to six months
  3. The ADVANCE II randomized, controlled, double-blind clinical trial6, which included review by an independent panel of surgeons

All three trials assessed the safety and efficacy of controlled delivery of mometasone furoate to the ethmoid sinus mucosa via dissolvable implants in chronic rhinosinusitis (CRS) patients undergoing functional endoscopic sinus surgery (FESS).    Safety Established in Clinical Studies:

  • Ocular safety demonstrated: No clinically significant changes from baseline in intraocular pressure or lens opacities occurred
  • Systemic safety demonstrated:  No evidence of systemic steroid exposure or adrenal-pituitary axis suppression

What to expect from Sinus Surgery:

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  1. Han JK, Marple BF, Smith TL et al. Int Forum Allergy Rhinol. 2012 ; 2 :271-279.
  2. Kennedy DW, Wright ED, Goldberg AN. Laryngoscope. 2000;110:29–31.
  3. Kennedy DW. Expert Review of Respiratory Medicine. 2012; 6(5):493-498.
  4. Murr AH, Smith TL, Hwang PH, et al. Int Forum Allergy Rhinol. 2011;1:23–32.
  5. Forwith KD, Chandra RK, Yun PT, Miller SK, Jampel HD. Laryngoscope. 2011;121:2473–2480.
  6. Marple BF, Smith TL, Han JK et al.  Otolaryngol Head Neck Surg.  2012; 146(6) 1004-1011.